Description

1H-Indole-2-Carbonyl Chloride,5-Fluoro- is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex, biologically active molecules. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the creation of novel therapeutic agents and agrochemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated indole-based drug candidates, including potential kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine atom enhances biological activity and stability.
• Material Science: Serves as a monomer or functionalization agent for creating specialized polymers and advanced organic electronic materials.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex heterocyclic frameworks and introducing the indole-2-carbonyl moiety into target molecules.
• Bioconjugation & Probe Development: Utilized to label biomolecules or create fluorescent probes and other diagnostic tools due to its reactive acid chloride group.

Basic Information

Product Name	1H-Indole-2-Carbonyl Chloride,5-Fluoro-
CAS No.	79112-09-7
Molecular Formula	C9H5ClFNO
Molecular Weight	197.59 g/mol
Synonyms	5-Fluoro-1H-indole-2-carbonyl chloride; 5-Fluoroindole-2-carbonyl chloride; 5-Fluoro-1H-indole-2-carboxylic acid chloride; 2-Carboxy-5-fluoroindole chloride; 5-Fluoro-2-indolecarbonyl chloride; 79112-09-7; 5-Fluoroindole-2-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Carbonyl Chloride,5-Fluoro- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.