Description

Griseolic Acid CAS NO 79030-08-3 is a biologically active secondary metabolite derived from microbial fermentation. This compound is of significant interest for its role as a potent and selective inhibitor of cyclic adenosine monophosphate (cAMP) phosphodiesterase. It serves as a critical biochemical tool for researchers and developers in the life sciences, enabling the study of cellular signaling pathways and enzyme function. Key industries that utilize this high-purity biochemical include pharmaceutical R&D, academic research institutions, and biotechnology companies focused on developing novel therapeutic agents.

Application

• Biochemical Research: Used as a selective inhibitor of cAMP phosphodiesterase (PDE) in enzymatic and cellular assays to study cAMP-mediated signaling pathways.
• Pharmaceutical Development: Serves as a reference standard and a lead compound in drug discovery programs targeting inflammatory diseases and central nervous system (CNS) disorders.
• Cell Biology Studies: Employed to investigate the role of cAMP in processes like cell proliferation, differentiation, and gene expression regulation.
• Enzyme Kinetics: Utilized as a tool compound to determine enzyme inhibition constants (Ki) and study the mechanism of PDE inhibition.
• Academic Research: A key reagent for universities and research institutes exploring cardiovascular, neurological, and metabolic disease models.
• Biotech Reagent Production: Incorporated into assay kits and research-grade biochemicals sold to the scientific community.

Basic Information

Product Name	Griseolic Acid
CAS No.	79030-08-3
Molecular Formula	C₁₄H₁₈N₄O₈
Molecular Weight	370.31 g/mol
Synonyms	Griseolic acid; 2,4,6,8-Tetrahydroxy-5-(1H-imidazol-5-yl)-3-methyl-1H,5H-pyrano[3,4-c]pyridine-1,7-dione; Antibiotic X-5108; NSC 339579; PDE Inhibitor Griseolic Acid; cAMP Phosphodiesterase Inhibitor
EINECS	Contact for details

Quality Control

Every batch of Griseolic Acid is manufactured and tested under strict quality management systems to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. Certificates of Analysis (COA) detailing batch-specific results for purity, identity, and impurities are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Biological Activity (PDE Inhibition)	Confirmed

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.