Description

4-Nitrophenyl 2-Azidobenzoate is a specialized bifunctional chemical intermediate that combines a photoreactive azido group with an activated ester moiety. This unique structure makes it a valuable reagent for photoaffinity labeling and bioconjugation strategies in advanced research and development. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for probing biomolecular interactions and developing novel diagnostic or therapeutic conjugates.

Application

• Photoaffinity Labeling Probe: A key reagent for crosslinking and identifying protein-ligand or protein-protein interactions in biochemical research.
• Bioconjugation Linker: Used to covalently attach molecules (e.g., drugs, fluorophores, peptides) to biological carriers or surfaces under controlled light activation.
• Polymer & Materials Science: Serves as a photo-crosslinker for modifying polymer backbones or creating light-responsive smart materials and hydrogels.
• Chemical Biology Tool: Enables the study of enzyme active sites and metabolic pathways through irreversible binding studies.
• Surface Functionalization: Applied in immobilizing biomolecules on chips, beads, or other substrates for biosensor development.
• Pharmaceutical Research Intermediate: Used in the synthesis of targeted drug delivery systems and investigational new chemical entities.

Basic Information

Product Name	4-Nitrophenyl 2-Azidobenzoate
CAS No.	78995-59-2
Molecular Formula	C₁₃H₈N₄O₄
Molecular Weight	284.23 g/mol
Synonyms	2-Azidobenzoic Acid 4-Nitrophenyl Ester; 4-Nitrophenyl o-Azidobenzoate; p-Nitrophenyl 2-Azidobenzoate; 2-Azidobenzoyl p-Nitrophenyl Ester; (2-Azidobenzoyloxy)benzene-4,1-diyl; PNPAzB; Photoaffinity Labeling Reagent 78995-59-2
EINECS	Contact for details

Quality Control

Our 4-Nitrophenyl 2-Azidobenzoate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management standards, and our processes are designed to meet the rigorous requirements of research and development laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. The compound is light-sensitive (store away from light). Keep container tightly sealed in a dry environment to minimize exposure to moisture. Store away from strong oxidizing agents and heat sources.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.