Description

Pyrazolo[1,5-A]Pyridine-3-Carbonyl Chloride is a versatile and highly reactive organic intermediate, specifically an acid chloride derivative of the pyrazolopyridine heterocyclic system. This compound is a critical building block in modern synthetic organic chemistry, enabling the efficient introduction of the pyrazolo[1,5-a]pyridine-3-carbonyl moiety into target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel small-molecule drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactive pyrazolopyridine scaffold.
• Material Science Research: Serves as a precursor for creating advanced organic materials, such as ligands for catalysts or components for organic electronic devices.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical suppliers and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	Pyrazolo[1,5-A]Pyridine-3-Carbonyl Chloride
CAS No.	78933-24-1
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	Pyrazolo[1,5-a]pyridine-3-carbonyl chloride; 1H-Pyrazolo[1,5-a]pyridine-3-carbonyl chloride; Pyrazolo[1,5-a]pyridine-3-carboxylic acid chloride; 3-Pyrazolo[1,5-a]pyridinecarbonyl chloride; 78933-24-1; Pyrazolopyridine-3-carbonyl chloride
EINECS	Contact for details

Quality Control

Our Pyrazolo[1,5-A]Pyridine-3-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of research and pre-clinical development stages in the pharmaceutical and chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.