Description

Bicyclo[3.2.0]Heptane-2-Carbonyl Chloride, 7-Oxo-, (1Alpha,2Alpha,5Alpha)- (9Ci) is a highly specialized and reactive bicyclic acid chloride derivative. This compound serves as a critical chiral building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of prostaglandins, prostacyclins, and other bioactive molecules with complex carbocyclic frameworks.
• Advanced Organic Synthesis: Used in stereoselective reactions, including nucleophilic acyl substitution and Friedel-Crafts acylation, to introduce the bicyclo[3.2.0]heptane scaffold.
• Medicinal Chemistry Research: A valuable precursor for creating focused libraries of compounds for drug discovery programs targeting various disease pathways.
• Chemical Biology Probes: Employed in the synthesis of activity-based probes and molecular tools for studying enzyme function and biological mechanisms.
• Material Science: Potential monomer or cross-linking agent for creating polymers with unique thermal and mechanical properties derived from its strained ring system.

Basic Information

Item	Details
Product Name	Bicyclo[3.2.0]Heptane-2-Carbonyl Chloride, 7-Oxo-, (1Alpha,2Alpha,5Alpha)- (9Ci)
CAS No.	78833-84-8
Molecular Formula	C9H9ClO2
Molecular Weight	184.62 g/mol
Synonyms	(1α,2α,5α)-7-Oxobicyclo[3.2.0]heptane-2-carbonyl chloride; (1R,2R,5R)-7-Oxobicyclo[3.2.0]heptane-2-carbonyl chloride; 7-Oxobicyclo[3.2.0]heptane-2-carbonyl chloride, (1α,2α,5α)-; Bicyclo[3.2.0]heptane-2-carbonyl chloride, 7-oxo-, (1α,2α,5α)-; (1Alpha,2Alpha,5Alpha)-7-Oxobicyclo[3.2.0]heptane-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our Bicyclo[3.2.0]Heptane-2-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and chiral purity analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and reactive acid chloride nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.