Description

3-Hydroxycholest-7-Ene-9-Carbonitrile is a high-purity steroidal nitrile derivative, a key synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the synthesis of novel steroid analogs and other bioactive molecules. It is primarily needed by pharmaceutical R&D teams, fine chemical manufacturers, and academic research laboratories focused on medicinal chemistry and steroid synthesis.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel steroid-based drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic agents targeting hormone receptors or metabolic pathways.
• Fine Chemical Synthesis: Serves as a versatile precursor for the preparation of specialized steroidal compounds with modified D-ring structures.
• Biochemical Probes: Potential use in developing molecular probes to study enzyme mechanisms or cellular processes involving sterol metabolism.
• Academic & Industrial R&D: Employed in exploratory organic synthesis for creating libraries of complex natural product analogs.

Basic Information

Product Name	3-Hydroxycholest-7-Ene-9-Carbonitrile
CAS No.	78806-56-1
Molecular Formula	C₂₈H₄₅NO
Molecular Weight	411.67 g/mol
Synonyms	9-Cyano-3-hydroxycholest-7-ene; Cholest-7-ene-9-carbonitrile, 3-hydroxy-; 3β-Hydroxycholest-7-en-9-carbonitrile; 3-Hydroxy-9-cyanocholest-7-ene; Steroid D-ring nitrile intermediate
EINECS	Contact for details

Quality Control

Our 3-Hydroxycholest-7-Ene-9-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0% (on anhydrous basis)
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.