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Strophanthidin-3-Tosyloxyacetate CAS NO 78730-59-3


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CAS No.:78730-59-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Strophanthidin-3-Tosyloxyacetate is a key chemical intermediate derived from the cardiac glycoside strophanthidin. This compound is of significant value in pharmaceutical research and development, particularly for the synthesis of novel cardioactive agents and for structure-activity relationship (SAR) studies. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of cardiovascular therapeutics and specialized organic synthesis.

Application

  • Pharmaceutical Intermediate: A crucial building block for the semi-synthesis of cardiac glycoside derivatives and other steroidal compounds with potential therapeutic activity.
  • Biochemical Research: Used as a reference standard or probe in studies investigating the mechanism of action of Na+/K+-ATPase inhibition and cardiac contractility.
  • Medicinal Chemistry: Serves as a versatile scaffold for the design and synthesis of new chemical entities targeting cardiovascular diseases.
  • Academic Research: Employed in university and institutional labs for studying steroid chemistry, glycoside modifications, and natural product derivatives.
  • Fine Chemical Synthesis: Used in multi-step organic syntheses requiring a functionalized steroidal core for further chemical transformations.

Basic Information

Product Name Strophanthidin-3-Tosyloxyacetate
CAS No. 78730-59-3
Molecular Formula C32H42O9S
Molecular Weight 602.74 g/mol
Synonyms 3β-[(p-Toluenesulfonyl)oxy]acetoxy-5β-strophanthidin; Strophanthidin 3-(p-toluenesulfonylacetate); Strophanthidin 3-tosyloxyacetate; 5β-Strophanthidin-3β-yl (p-toluenesulfonyl)acetate; 3β-[(p-Toluenesulfonyloxy)acetyloxy]-5β-strophanthidin; (3β,5β)-3-[[[(4-Methylphenyl)sulfonyl]oxy]acetyl]oxy]-14-hydroxy-19-oxocard-20(22)-enolide; Strophanthidin tosyloxyacetate
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Quality Control

Our Strophanthidin-3-Tosyloxyacetate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light).

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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