Description

3-(Aminocarbonyl)-1-β-D-Ribofuranosylpyridinium Bromide is a specialized nucleoside derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a crucial building block and precursor for synthesizing novel nicotinamide adenine dinucleotide (NAD+) analogs and other bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in metabolic pathway studies, enzyme cofactor research, and the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of NAD+ analogs and other nucleotide-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Essential reagent for studying enzymatic mechanisms, particularly those involving dehydrogenases and sirtuins.
• Metabolomics & Cell Biology: Used as a tool compound to investigate cellular metabolism, redox states, and energy pathways.
• Enzyme Cofactor Development: Serves as a scaffold for creating novel cofactors and probes for diagnostic and therapeutic applications.
• Academic & Industrial R&D: Employed in discovery chemistry for developing new chemical entities targeting age-related diseases and metabolic disorders.

Basic Information

Product Name	3-(Aminocarbonyl)-1-β-D-Ribofuranosylpyridinium Bromide
CAS No.	78687-39-5
Molecular Formula	C11H15BrN2O6
Molecular Weight	351.15 g/mol
Synonyms	1-(β-D-Ribofuranosyl)-3-carbamoylpyridinium Bromide; Nicotinamide Riboside Bromide; NR Bromide; 3-Carbamoyl-1-(β-D-ribofuranosyl)pyridinium Bromide; 1-(β-D-Ribofuranosyl)nicotinamide Bromide; Pyridinium, 3-(aminocarbonyl)-1-β-D-ribofuranosyl-, bromide; 3-Carbamoylpyridinium Riboside Bromide
EINECS	Contact for details

Quality Control

Our 3-(Aminocarbonyl)-1-β-D-Ribofuranosylpyridinium Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.