Description

5-Bromo-6-Chloronicotinoyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound matters because it serves as a critical building block for constructing complex heterocyclic molecules, enabling the development of novel active ingredients. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for nicotinic acid derivatives and other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, insecticides, and fungicides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and organic semiconductors.
• Chemical Biology Probes: Acts as a versatile scaffold for creating molecular probes and labeled compounds used in biochemical and diagnostic research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated nicotinoyl derivatives.

Basic Information

Product Name	5-Bromo-6-Chloronicotinoyl Chloride
CAS No.	78686-84-7
Molecular Formula	C7H2BrCl2NO
Molecular Weight	274.91 g/mol
Synonyms	5-Bromo-6-chloropyridine-3-carbonyl chloride; 3-Pyridinecarbonyl chloride, 5-bromo-6-chloro-; 5-Bromo-6-chloronicotinic acid chloride; 5-Bromo-6-chloro-3-pyridinecarboxylic acid chloride; Nicotinoyl chloride, 5-bromo-6-chloro-
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Chloronicotinoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.