Description

(3β,5β,7α,12α)-3,7,12-Trihydroxy-Cholestan-26-Oic Acid CAS NO 78608-74-9 is a high-purity, crystalline bile acid derivative, a key intermediate in the synthesis of critical pharmaceutical compounds. Its defined stereochemistry and functional groups make it an essential building block for research and production in advanced therapeutic areas. This compound is primarily required by manufacturers and R&D laboratories in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of therapeutic bile acids and steroid-based pharmaceuticals.
• Biochemical Research: Used as a reference standard and reagent in metabolic pathway studies, particularly those involving cholesterol and bile acid metabolism.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key chiral starting material for the production of complex, high-value APIs targeting liver and metabolic disorders.
• Diagnostic Agent Development: Employed in the research and development of diagnostic assays and contrast agents related to hepatobiliary function.
• Cell Culture & Media Supplement: Utilized in specialized cell culture applications to study membrane fluidity and cellular signaling pathways.

Basic Information

Item	Details
Product Name	(3β,5β,7α,12α)-3,7,12-Trihydroxy-Cholestan-26-Oic Acid
CAS No.	78608-74-9
Molecular Formula	C27H46O5
Molecular Weight	450.66 g/mol
Synonyms	3α,7α,12α-Trihydroxy-5β-cholestan-26-oic acid; 3α,7α,12α-Trihydroxy-5β-cholan-26-oic acid; Trihydroxycholestanoic acid; THCA; (25R)-3α,7α,12α-Trihydroxy-5β-cholestan-26-oic Acid
EINECS	Contact for details

Quality Control

Every batch of (3β,5β,7α,12α)-3,7,12-Trihydroxy-Cholestan-26-Oic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation to support your regulatory and research needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are prepared in accordance with current industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.