Description

3-Deaza-2'-Deoxyadenosine is a chemically modified nucleoside analog, a valuable building block and research tool in medicinal chemistry and biochemistry. Its unique structure, where a nitrogen atom in the adenine ring is replaced by a carbon atom, makes it a critical intermediate for synthesizing novel antiviral and anticancer agents. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors, particularly those focused on nucleoside-based drug discovery and nucleic acid research.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a tool compound to study enzyme mechanisms, particularly those involving S-adenosylhomocysteine hydrolase and other methyltransferases.
• Antiviral Agent Development: Serves as a core scaffold for developing compounds targeting viral replication.
• Life Science Reagents: Incorporated into oligonucleotides for research into nucleic acid structure, function, and stability.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to optimize the potency and selectivity of drug candidates.
• Academic Research: Employed in university and institutional labs for fundamental studies in epigenetics and cellular signaling pathways.

Basic Information

Product Name	3-Deaza-2'-Deoxyadenosine
CAS No.	78582-17-9
Molecular Formula	C11H14N4O3
Molecular Weight	250.26 g/mol
Synonyms	3-Deaza-2'-deoxyadenosine; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-3H-imidazo[4,5-c]pyridin-4-amine; 3-Deaza-dA; 3-Deaza-2'-deoxyadenosine; 3-Deaza-2'-deoxyadenosine; 3-Deaza-2'-deoxyadenosine (3-Deaza-dA); 3-Deaza-2'-deoxyadenosine nucleoside
EINECS	Contact for details

Quality Control

Our 3-Deaza-2'-Deoxyadenosine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.