Description

2-Oxabicyclo[2.2.1]Heptane-1-Carbonyl Chloride, 7,7-Dimethyl-3-Oxo-, (1R)- (9Ci) is a high-purity, chiral bicyclic building block of significant interest in advanced organic synthesis. Its unique, rigid molecular framework and reactive acid chloride functionality make it a critical intermediate for constructing complex, stereodefined molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its bicyclic structure can contribute to unique biological activity and selectivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of sophisticated chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical & Specialty Material Production: Employed in the manufacture of complex fragrances, flavors, and other high-value specialty chemicals requiring precise stereochemistry.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis, enabling the exploration of new reaction pathways and molecular architectures.

Basic Information

Product Name	2-Oxabicyclo[2.2.1]Heptane-1-Carbonyl Chloride, 7,7-Dimethyl-3-Oxo-, (1R)- (9Ci)
CAS No.	78436-33-6
Molecular Formula	C9H11ClO3
Molecular Weight	202.64 g/mol
Synonyms	(1R)-7,7-Dimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride; (1R)-Camphor-10-sulfonyl chloride (related structure); 1R-7,7-Dimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride; Bicyclo[2.2.1]heptane-1-carbonyl chloride, 2-oxa-7,7-dimethyl-3-oxo-, (1R)-; (1R)-(+)-7,7-Dimethyl-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride, 3-oxo-; Chiral Camphor Sulfonyl Chloride Analog; (1R)-10-Camphorsulfonyl chloride derivative
EINECS	Contact for details

Quality Control

Our 2-Oxabicyclo[2.2.1]Heptane-1-Carbonyl Chloride, 7,7-Dimethyl-3-Oxo-, (1R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.