Description

Ethenoadenylyl Imidodiphosphate is a high-purity biochemical reagent, specifically a non-hydrolyzable ATP analog, crucial for research in enzymology and signal transduction. Its core value lies in its ability to irreversibly bind to ATP-binding sites, making it an essential tool for studying kinase and ATPase mechanisms. This product is primarily needed by researchers and manufacturers in the life sciences sector, including pharmaceutical R&D, academic biochemistry laboratories, and diagnostic kit development.

Application

• Enzyme Kinetics Research: Used as a substrate analog to study the mechanisms of ATP-dependent enzymes like kinases, ATPases, and synthetases.
• Signal Transduction Studies: Employed to investigate phosphorylation cascades and cellular signaling pathways by locking proteins in an activated state.
• Pharmaceutical Screening: Serves as a key reagent in high-throughput screening assays to identify potential inhibitors of ATP-binding proteins.
• Structural Biology: Utilized in X-ray crystallography and NMR studies to obtain structural data of enzyme-ligand complexes.
• Diagnostic Development: Acts as a component in the development of biochemical assays for clinical diagnostics and research kits.
• Metabolic Pathway Analysis: Applied in studies to dissect and understand complex metabolic networks involving ATP.

Basic Information

Product Name	Ethenoadenylyl Imidodiphosphate
CAS No.	78368-53-3
Molecular Formula	C12H16N5O12P3
Molecular Weight	539.19 g/mol
Synonyms	Adenosine 5'-(β,γ-imido)triphosphate, 1,N6-Ethenoadenosine 5'-triphosphate, ε-ATP, Etheno-ATP, 1,N6-Ethenoadenosine-5'-triphosphate, ATP-γ-imidophosphate, Adenosine 5'-[γ-imido]triphosphate, Adenylyl imidodiphosphate etheno derivative
EINECS	Contact for details

Quality Control

Our Ethenoadenylyl Imidodiphosphate is manufactured under strict quality protocols to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic nature, the container should be allowed to equilibrate to room temperature before opening to minimize moisture uptake. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Biological Activity	Tested in standard kinase assay
Solubility	Soluble in water or buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.