Description

5-Phenylisoxazole-3-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its core value lies in its acyl chloride functionality, which enables efficient coupling reactions to construct complex heterocyclic scaffolds. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing potential drug candidates, particularly those containing the isoxazole pharmacophore.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for creating specialized polymers or organic electronic materials.
• Peptide Mimetics & Conjugation: Facilitates the introduction of the phenylisoxazole moiety into peptides or proteins for biochemical studies.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and novel compound library generation.
• Fine Chemical Production: Integral in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	5-Phenylisoxazole-3-Carbonyl Chloride
CAS No.	78189-50-1
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	5-Phenyl-3-isoxazolecarbonyl chloride; 3-Isoxazolecarbonyl chloride, 5-phenyl-; 5-Phenylisoxazole-3-carboxylic acid chloride; 5-Phenyl-1,2-oxazole-3-carbonyl chloride; 78189-50-1; 5-Phenylisoxazolyl-3-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 5-Phenylisoxazole-3-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.