Description

Ara-Tubercidin 5'-Triphosphate is a chemically modified nucleotide analog of significant interest in biochemical research. This compound serves as a critical tool for studying enzyme mechanisms, particularly those involving ATP-dependent processes, due to its structural similarity to adenosine triphosphate (ATP). It is primarily utilized by research scientists and pharmaceutical developers in the fields of molecular biology, enzymology, and medicinal chemistry for investigating nucleotide metabolism and as a potential probe for targeted therapeutic applications.

Application

• Enzymology Research: Used as a substrate analog to study the kinetics and inhibition of ATP-dependent enzymes, including kinases, polymerases, and helicases.
• Mechanistic Biochemistry: Employed in probing the active sites and catalytic mechanisms of nucleotide-binding proteins to understand disease pathways.
• Medicinal Chemistry & Drug Discovery: Serves as a lead compound or biochemical tool for developing novel antiviral or anticancer agents targeting nucleotide metabolism.
• Molecular Biology Assays: Utilized in in vitro assays to investigate DNA/RNA synthesis and repair mechanisms where natural ATP analogs are required.
• Biochemical Probe Development: Acts as a specialized reagent for labeling or cross-linking studies to map protein-nucleotide interactions.

Basic Information

Product Name	Ara-Tubercidin 5'-Triphosphate
CAS No.	78153-66-9
Molecular Formula	C₁₅H₂₃N₅O₁₃P₃
Molecular Weight	622.28 g/mol
Synonyms	1-β-D-Arabinofuranosyl-7-deazaadenosine 5'-triphosphate; 7-Deaza-ara-ATP; Ara-7-deazaadenosine triphosphate; 1-(β-D-Arabinofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 5'-(trihydrogen triphosphate); Tubercidin arabinoside triphosphate; Ara-tubercidin TP; 7-Deaza-1-β-D-arabinofuranosyladenine 5'-triphosphate
EINECS	Contact for details

Quality Control

Our Ara-Tubercidin 5'-Triphosphate is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and structural confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (Karl Fischer)	≤ 5.0%
Solubility	Soluble in water or appropriate aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.