Description

n-Fructosylamphotericin B is a glycosylated derivative of the potent polyene macrolide antifungal agent, amphotericin B. This modification is designed to potentially alter the compound's solubility, pharmacokinetic profile, and therapeutic index, making it a subject of significant research interest. It is primarily utilized in advanced pharmaceutical research and development for exploring novel antifungal therapies and targeted drug delivery systems.

Application

• Pharmaceutical R&D for novel antifungal drug candidates.
• Investigation into improved solubility and reduced toxicity profiles compared to amphotericin B.
• Preclinical studies for targeted drug delivery mechanisms.
• Bioconjugation research and prodrug development.
• As a reference standard in analytical method development and quality control.
• Academic research in medicinal chemistry and pharmacology.

Basic Information

Product Name	n-Fructosylamphotericin B
CAS No.	78107-92-3
Molecular Formula	C47H73NO17 (Amphotericin B core + Fructose)
Molecular Weight	~ 924.09 g/mol (Contact for exact details)
Synonyms	Amphotericin B Fructoside; Fructosyl-AmB; 1-Deoxy-1-(amphotericin B-ylamino)-D-fructose; Amphotericin B N-fructosyl derivative; Polyene antibiotic derivative; Antifungal research compound; Glycosylated amphotericin B
EINECS	Contact for details

Quality Control

Our n-Fructosylamphotericin B is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements of research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.