Description

(3,4-Dimethoxy-Benzyl)-Phosphonic Acid Diethyl Ester is a high-purity organophosphorus compound that serves as a versatile synthetic intermediate and building block. Its molecular structure, featuring a phosphonic acid diethyl ester group attached to a dimethoxy-substituted benzyl ring, makes it valuable for constructing complex molecules in advanced research and development. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and ligand synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that utilize phosphonate chemistry.
• Ligand Synthesis: Serves as a precursor for phosphonate- and phosphine-based ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the creation of molecular probes and tool compounds for studying enzyme function and biological pathways.
• Material Science: Potential monomer or additive in the development of specialty polymers and flame-retardant materials.
• Process Chemistry: Used in route scouting and optimization for the scalable production of complex organic molecules.

Basic Information

Product Name	(3,4-Dimethoxy-Benzyl)-Phosphonic Acid Diethyl Ester
CAS No.	78055-65-9
Molecular Formula	C13H21O5P
Molecular Weight	288.28 g/mol
Synonyms	Diethyl (3,4-Dimethoxybenzyl)phosphonate; (3,4-Dimethoxybenzyl)phosphonic Acid Diethyl Ester; Diethyl (3,4-Dimethoxyphenylmethyl)phosphonate; Phosphonic Acid, P-[(3,4-Dimethoxyphenyl)methyl]-, Diethyl Ester; Veratrylphosphonic Acid Diethyl Ester; 3,4-Dimethoxybenzylphosphonic Acid Diethyl Ester; Diethyl Veratrylphosphonate
EINECS	Contact for details

Quality Control

Our (3,4-Dimethoxy-Benzyl)-Phosphonic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the stringent requirements of research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.