Description

4-Azidobenzoylglycylhydrazide is a specialized organic compound featuring a reactive azide group and a hydrazide moiety, making it a valuable bifunctional linker and building block in advanced chemical synthesis. Its core value lies in enabling efficient conjugation and cross-linking reactions, particularly through click chemistry and amide bond formation. This compound is essential for researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science industries who require precise molecular assembly for developing novel therapeutics, probes, and functional polymers.

Application

• Bioconjugation Reagent: Used as a heterobifunctional cross-linker for attaching molecules (e.g., drugs, dyes, polymers) to proteins, antibodies, or other biomolecules.
• Click Chemistry Intermediate: Serves as a key precursor in Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for constructing complex molecular architectures.
• Pharmaceutical Research: Employed in the synthesis of targeted drug delivery systems and antibody-drug conjugates (ADCs) due to its selective reactivity.
• Polymer Functionalization: Used to introduce reactive azide groups into polymer backbones for subsequent modification or cross-linking.
• Proteomics & Chemical Biology: Acts as a probe or affinity tag for labeling and studying protein function and interactions.
• Materials Science: Facilitates the surface modification of nanoparticles and other nanomaterials for specific applications.
• Diagnostic Reagent Synthesis: A building block for creating contrast agents or labeled compounds used in imaging and diagnostics.

Basic Information

Product Name	4-Azidobenzoylglycylhydrazide
CAS No.	77889-73-7
Molecular Formula	C9H10N6O2
Molecular Weight	234.22 g/mol
Synonyms	p-Azidobenzoylglycylhydrazide; 4-Azidobenzoyl-Gly-Hydrazide; Glycine, N-[(4-azidobenzoyl)hydrazide]; N-[(4-Azidobenzoyl)hydrazino]acetamide; Azido-PEG1-acid hydrazide; ABGH; (4-Azidobenzamido)acetohydrazide
EINECS	Contact for details

Quality Control

Our 4-Azidobenzoylglycylhydrazide is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. The compound is light-sensitive and should be handled under appropriate conditions to minimize degradation. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.