Description

Cyclopropanecarbonyl Chloride, 3-Acetyl-2,2-Dimethyl-, trans- (9Ci) is a specialized organic intermediate featuring a reactive acid chloride group and a cyclopropane ring system. This compound matters as a high-value building block for the synthesis of complex molecules, enabling the introduction of the unique, strained cyclopropane moiety into target structures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing unique steric properties.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the cyclopropane ring can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored mechanical or thermal properties.
• Ligand and Catalyst Development: Employed to create sophisticated chiral ligands or organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme mechanisms or protein interactions.
• Fine Chemical Production: Acts as a precursor for other high-value, functionalized cyclopropane derivatives used in various niche applications.

Basic Information

Product Name	Cyclopropanecarbonyl Chloride, 3-Acetyl-2,2-Dimethyl-, trans- (9Ci)
CAS No.	77772-08-8
Molecular Formula	C8H11ClO2
Molecular Weight	174.62 g/mol
Synonyms	trans-3-Acetyl-2,2-dimethylcyclopropanecarbonyl chloride; (1R,3S)-3-Acetyl-2,2-dimethylcyclopropanecarbonyl chloride; 2,2-Dimethyl-3-oxocyclopropanecarboxylic acid chloride; 3-Acetyl-2,2-dimethylcyclopropanecarboxylic acid chloride; Cyclopropanecarbonyl chloride, 3-acetyl-2,2-dimethyl-, trans-; 77772-08-8; (1S,3R)-3-Acetyl-2,2-dimethylcyclopropanecarbonyl chloride
EINECS	Contact for details

Quality Control

Our Cyclopropanecarbonyl Chloride, 3-Acetyl-2,2-Dimethyl-, trans- (9Ci) is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure high purity and consistent performance as a synthetic intermediate. Certificates of Analysis (COA) detailing identity, purity (typically by GC or HPLC), and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Contact for specific grade purity)
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.