Description

2'-Deoxycytidylyl(3'5')-Thymidineammoniu M is a chemically modified dinucleotide derivative, a key building block in advanced oligonucleotide synthesis. This compound is critical for researchers and manufacturers developing next-generation therapeutic and diagnostic nucleic acid products, where precise chemical modification is required to enhance stability, specificity, and delivery. It is primarily utilized by the pharmaceutical, biotechnology, and life sciences research sectors for applications in antisense oligonucleotides, siRNA, and other sophisticated molecular biology tools.

Application

• Pharmaceutical Intermediate: A crucial building block for the solid-phase synthesis of therapeutic oligonucleotides, including antisense drugs and siRNA.
• Research Reagent: Used in academic and industrial R&D for studying nucleic acid structure, function, and for developing novel gene-silencing technologies.
• Diagnostic Probe Synthesis: Employed in the manufacture of labeled probes for molecular diagnostics, such as FISH (Fluorescence In Situ Hybridization) and PCR-based assays.
• Antisense Technology: Integral to creating modified oligonucleotides with enhanced nuclease resistance and binding affinity for target mRNA sequences.
• Bioconjugation: Serves as a starting point for further chemical modifications to attach reporter molecules, peptides, or other functional groups.

Basic Information

Product Name	2'-Deoxycytidylyl(3'5')-Thymidineammoniu M
CAS No.	77710-60-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	d(CpT) Ammonium Salt; 2'-Deoxycytidylyl-(3'→5')-thymidine ammonium salt; Cytidylyl(3'-5')thymidine ammonium derivative; Dinucleotide CpT ammonium salt; 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxycytidylyl-(3'→5')-thymidine 3'-(2-cyanoethyl N,N-diisopropylphosphoramidite) (related precursor); dCpT-NH4+; Ammonium 2'-deoxycytidylyl(3',5')thymidine
EINECS	Contact for details

Quality Control

Our 2'-Deoxycytidylyl(3'5')-Thymidineammoniu M is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical and high-end research applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.