Description

D-Ribitol, 1-C-(4-Amino-5H-Pyrrolo[3,2-d]pyrimidin-7-Yl)-1,4-Anhydro-, (1S)- is a sophisticated nucleoside analogue derivative, representing a key building block in advanced pharmaceutical research and development. This compound is valued for its role as a precursor or intermediate in the synthesis of novel antiviral and anticancer agents, particularly those targeting nucleic acid metabolism. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of next-generation therapeutics, where high-purity, well-characterized intermediates are critical for successful outcomes.

Application

• Pharmaceutical Intermediate: Serves as a critical synthetic precursor for the development of novel nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleoside and nucleotide metabolism pathways.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the efficacy and selectivity of therapeutic candidates.
• Antiviral Agent Development: A key scaffold in the research of compounds designed to interfere with viral replication mechanisms.
• Labeled Compound Synthesis: Can be used as a starting point for synthesizing isotopically labeled versions for pharmacokinetic and metabolic tracing studies.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry and bioorganic mechanisms.

Basic Information

Product Name	D-Ribitol, 1-C-(4-Amino-5H-Pyrrolo[3,2-d]pyrimidin-7-Yl)-1,4-Anhydro-, (1S)-
CAS No.	77691-03-3
Molecular Formula	C11H14N4O4
Molecular Weight	266.25 g/mol
Synonyms	(1S)-1-C-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-1,4-anhydro-D-ribitol; 7-(1,4-Anhydro-1-C-D-ribitol-1-yl)-4-amino-5H-pyrrolo[3,2-d]pyrimidine; 4-Amino-7-((1S,2R,3S,4R)-2,3,4-trihydroxycyclopentyl)-5H-pyrrolo[3,2-d]pyrimidine; Carbocyclic nucleoside analogue intermediate; c-Nucleoside derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our D-Ribitol, 1-C-(4-Amino-5H-Pyrrolo[3,2-d]pyrimidin-7-Yl)-1,4-Anhydro-, (1S)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic and spectral data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.