Description

(20R)-Pregn-5-Ene-3β,11α,12β,14,20-Pentol 11-(3-Methyl-2-Butenoate) is a high-purity, semi-synthetic steroid derivative with a complex pentol structure. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential as a key intermediate or reference standard. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, metabolic studies, and analytical method development. Our supply ensures consistent quality and reliable availability for critical R&D and manufacturing processes.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of specialized steroid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method validation, calibration, and impurity profiling.
• Biochemical Research: Employed in academic and industrial research to study steroid metabolism, receptor interactions, and enzymatic pathways.
• Process Development: Acts as a starting material or intermediate for optimizing synthetic routes and scaling up production of target molecules.
• Metabolite Synthesis: Utilized for the preparation of potential drug metabolites for pharmacological and toxicological evaluation.

Basic Information

Product Name	(20R)-Pregn-5-Ene-3β,11α,12β,14,20-Pentol 11-(3-Methyl-2-Butenoate)
CAS No.	77524-37-9
Molecular Formula	C₂₆H₄₀O₇
Molecular Weight	464.59 g/mol
Synonyms	11α,12β,14,20-Tetrahydroxypregn-5-en-3β-yl 3-methylbut-2-enoate; 3β,11α,12β,14,20-Pentahydroxypregn-5-ene 11-(3-methyl-2-butenoate); 11α-Hydroxy-12β,14,20-trihydroxypregn-5-en-3β-yl 3,3-dimethylacrylate; Pregn-5-ene-3β,11α,12β,14,20-pentol 11-(3-methylbut-2-enoate); 3β,11α,12β,14,20-Pentahydroxy-5-pregnene 11-angelate; A related steroid pentol angelate.
EINECS	Contact for details

Quality Control

Our (20R)-Pregn-5-Ene-3β,11α,12β,14,20-Pentol 11-(3-Methyl-2-Butenoate) is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and specific impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.