Description

Nikkomycin N CAS NO 77368-58-2 is a potent nucleoside-peptide antibiotic belonging to the nikkomycin family, which acts as a competitive inhibitor of chitin synthase. This compound is of significant interest in biochemical and pharmaceutical research due to its specific mode of action against fungi and insects. It is primarily utilized by researchers and developers in the life sciences sector for antifungal studies, agricultural research, and as a key reference standard in analytical laboratories.

Application

• Antifungal Research & Development: Serves as a critical tool compound for studying chitin biosynthesis inhibition and screening for novel fungicides.
• Agricultural Science: Investigated for its potential as a bio-rational pesticide targeting chitin-containing pests.
• Biochemical Studies: Used in enzymatic assays to understand the structure and function of chitin synthases.
• Pharmaceutical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in laboratories.
• Microbiology: Applied in studies of fungal cell wall composition and integrity.

Basic Information

Product Name	Nikkomycin N
CAS No.	77368-58-2
Molecular Formula	C20H28N6O9
Molecular Weight	496.47 g/mol
Synonyms	Nikkomycin N; Antibiotic Z 4440; Z-4440; Nikkomycin N Antibiotic; (2S,3S,4R,5R)-5-[(2-Amino-4-hydroxy-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl]-3,4-dihydroxy-N-[(2R,3R)-3-hydroxy-2-[(1-methyl-4-oxo-4,5-dihydro-1H-imidazol-5-yl)amino]butanoyl]oxolane-2-carboxamide
EINECS	Contact for details

Quality Control

Our Nikkomycin N is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.