Description

5-((Cyanomethylene)Oxy)-2'-Deoxyuridine is a chemically modified nucleoside analog, a key building block in advanced pharmaceutical and biochemical research. This compound is valued for its unique structure, which allows it to act as a potent inhibitor or a substrate analog in enzymatic studies, particularly those involving viral polymerases and DNA synthesis pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel antiviral agents, anticancer therapeutics, and molecular probes.

Application

• Antiviral Drug Research: Serves as a critical intermediate in the synthesis and development of nucleoside-based antiviral compounds targeting viruses like herpes simplex and cytomegalovirus.
• Oncology Research: Used in the study and development of chemotherapeutic agents that interfere with DNA replication in cancer cells.
• Biochemical Probes: Acts as a substrate or inhibitor in enzymatic assays to study the mechanisms of DNA polymerases and related enzymes.
• Nucleic Acid Chemistry: Employed as a specialized monomer for the chemical synthesis of modified oligonucleotides with specific functional properties.
• Academic & Pharmaceutical R&D: A fundamental reagent for medicinal chemistry programs focused on modifying nucleoside scaffolds to enhance drug efficacy and reduce toxicity.

Basic Information

Product Name	5-((Cyanomethylene)Oxy)-2'-Deoxyuridine
CAS No.	77355-97-6
Molecular Formula	C11H11N3O6
Molecular Weight	281.22 g/mol
Synonyms	5-Cyanomethoxymethyl-2'-deoxyuridine; 5-[(Cyanomethoxy)methyl]-2'-deoxyuridine; 5-(Cyanomethoxymethyl)-2'-deoxyuridine; 2'-Deoxy-5-[(cyanomethoxy)methyl]uridine; 5-(Cyanomethyleneoxy)-2'-deoxyuridine; NSC 339638; 5-CMM-dUrd
EINECS	Contact for details

Quality Control

Our 5-((Cyanomethylene)Oxy)-2'-Deoxyuridine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research-grade chemicals, and custom purity grades can be supplied to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.