Description

Gannibamycin CAS NO 77271-98-8 is a specialized antibiotic compound belonging to the ansamycin class, characterized by its unique macrocyclic lactam structure. This product is critical for research and development in combating resistant bacterial strains, offering a valuable tool for microbiological studies and novel therapeutic exploration. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on infectious disease and antimicrobial discovery.

Application

• Antimicrobial Research: Serves as a key reference standard and active agent in studies targeting Gram-positive bacteria and mycobacteria.
• Pharmaceutical Development: Used in the synthesis and screening of new antibiotic derivatives and combination therapies.
• Mechanistic Studies: Employed to investigate bacterial RNA polymerase inhibition and the mechanisms of ansamycin-class antibiotics.
• Microbiological Assays: Acts as a positive control in potency testing and susceptibility assays within quality control laboratories.
• Academic Research: A fundamental reagent for university and institutional research into bacterial genetics and resistance pathways.

Basic Information

Product Name	Gannibamycin
CAS No.	77271-98-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Gannibamycin; Antibiotic K 4; Antibiotic K-4; Ansamycin K 4; K-4 Antibiotic; 2,15-Epoxy-19,21,23-trimethoxy-7,9,28-trimethyl-17,27-epoxy-7,22:15,28-dimetheno-2H,17H-pyrido[2,1-f][1,7,19]oxadiazacyclotetracosine-4,11,16,25(1H,3H,12H)-tetrone
EINECS	Contact for details

Quality Control

Our Gannibamycin is produced and tested under a rigorous quality management system. Each batch is analyzed to ensure identity, purity, and potency, with testing typically including identification by spectroscopic methods, chromatographic purity assays, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.