Description

N6-Benzoyl-2',3'-Dideoxyadenosine is a chemically modified nucleoside derivative, specifically an N6-benzoylated 2',3'-dideoxyadenosine analog. This compound serves as a crucial synthetic intermediate and building block in advanced organic and medicinal chemistry research. It is primarily utilized by research scientists and process development chemists in the pharmaceutical, biotechnology, and life sciences sectors for the synthesis of nucleotide analogs and prodrug development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of modified nucleoside analogs and potential antiviral or anticancer prodrugs.
• Biochemical Research: Used in studies investigating nucleotide metabolism, enzyme inhibition, and structure-activity relationships (SAR).
• Antiviral Drug Development: Serves as a precursor in the research and development of dideoxynucleoside-based therapeutic agents.
• Organic Synthesis: Valuable intermediate for introducing protected adenine moieties into complex molecular architectures.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for nucleotide-derived Active Pharmaceutical Ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental studies in nucleic acid chemistry and medicinal chemistry.

Basic Information

Product Name	N6-Benzoyl-2',3'-Dideoxyadenosine
CAS No.	77244-86-1
Molecular Formula	C₁₇H₁₇N₅O₃
Molecular Weight	339.35 g/mol
Synonyms	N6-Benzoyl-2',3'-ddA; 2',3'-Dideoxy-N6-benzoyladenosine; 9-[(2R,5S)-5-(Hydroxymethyl)oxolan-2-yl]-N-phenyl-9H-purin-6-amine; Bz-ddA; N6-Benzoyl-2',3'-dideoxyadenosine; 2',3'-Dideoxyadenosine, N6-benzoyl-; Adenosine, 2',3'-dideoxy-, N6-benzoate
EINECS	Contact for details

Quality Control

Our N6-Benzoyl-2',3'-Dideoxyadenosine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.