Description

1-β-Arabinofuranosyl-5-(2-Chlorovinyl)Uracil is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound matters as a key synthetic intermediate or potential active pharmaceutical ingredient (API) for antiviral and anticancer therapies. It is primarily needed by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of novel nucleoside-based therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand nucleoside metabolism and related biological pathways.
• Antiviral Agent Development: Investigated for its potential activity against DNA viruses, including herpesviruses, due to its structural similarity to other active nucleoside analogs.
• Oncology Research: Explored in preclinical studies for its cytotoxic properties and potential to inhibit cancer cell proliferation.
• Prodrug Synthesis: Acts as a core structure for the development of prodrugs aimed at improving bioavailability and targeted delivery.
• Reference Standard: Supplied as a high-purity compound for use as an analytical reference standard in quality control laboratories.

Basic Information

Product Name	1-β-Arabinofuranosyl-5-(2-Chlorovinyl)Uracil
CAS No.	77181-70-5
Molecular Formula	C11H11ClN2O6
Molecular Weight	302.67 g/mol
Synonyms	5-(2-Chlorovinyl)-1-β-D-arabinofuranosyluracil; 1-β-D-Arabinofuranosyl-5-(2-chlorovinyl)uracil; 5-(2-Chlorovinyl)arabinofuranosyluracil; BV-araU; Sorivudine Impurity; (E)-5-(2-Chlorovinyl)-1-β-D-arabinofuranosyluracil; 1-(β-D-Arabinofuranosyl)-5-[(E)-2-chlorovinyl]uracil
EINECS	Contact for details

Quality Control

Our 1-β-Arabinofuranosyl-5-(2-Chlorovinyl)Uracil is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.