Description

1,4-Benzodioxin-2-Carbonyl Chloride, 2,3-Dihydro-, (+)- (9Ci) is a high-purity chiral building block and key synthetic intermediate. This compound is valued for its role in constructing complex molecular architectures, particularly in the synthesis of enantiomerically pure pharmaceuticals and advanced materials. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of enantiomerically pure active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced, targeted pesticides and herbicides requiring specific stereochemistry.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialized polymers and organic electronic materials with defined optical properties.
• Academic & Industrial R&D: A valuable tool for medicinal chemistry programs and process chemistry optimization in laboratory-scale and pilot-plant settings.

Basic Information

Product Name	1,4-Benzodioxin-2-Carbonyl Chloride, 2,3-Dihydro-, (+)- (9Ci)
CAS No.	77156-54-8
Molecular Formula	C9H7ClO3
Molecular Weight	198.60 g/mol
Synonyms	(+)-2,3-Dihydro-1,4-benzodioxin-2-carbonyl chloride; (2R)-2,3-Dihydro-1,4-benzodioxine-2-carbonyl chloride; (R)-(+)-2,3-Dihydrobenzo[b][1,4]dioxine-2-carbonyl chloride; 1,4-Benzodioxin-2-carbonyl chloride, 2,3-dihydro-, (R)-; (R)-2,3-Dihydro-1,4-benzodioxine-2-carbonyl chloride; Chiral benzodioxane carbonyl chloride; 2,3-Dihydro-1,4-benzodioxin-2-carbonyl chloride, (+)-
EINECS	Contact for details

Quality Control

Our production of 1,4-Benzodioxin-2-Carbonyl Chloride, 2,3-Dihydro-, (+)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical purity, and identity confirmation. We are committed to meeting the exacting standards required for pharmaceutical R&D and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with strong acids and organic solvents; it must be kept under an inert atmosphere (e.g., nitrogen or argon) and isolated from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.