Description

1,4-Benzodioxin-2-Carbonyl Chloride, 2,3-Dihydro-, (-)- (9Ci) is a high-purity, chiral chemical intermediate characterized by its reactive carbonyl chloride functional group. This compound is critical for the synthesis of complex molecules where stereochemical control is paramount, offering researchers and manufacturers a reliable building block for advanced chemical development. It is primarily sought after by the pharmaceutical and agrochemical industries for the production of active ingredients and novel compounds requiring specific enantiomeric purity.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug research.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and pesticides for enhanced efficacy and environmental safety.
• Ligand and Catalyst Preparation: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel polymers and functional materials with specific optical or electronic properties.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and the exploration of new synthetic pathways.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	1,4-Benzodioxin-2-Carbonyl Chloride, 2,3-Dihydro-, (-)- (9Ci)
CAS No.	77156-53-7
Molecular Formula	C9H7ClO3
Molecular Weight	198.60 g/mol
Synonyms	(-)-2,3-Dihydro-1,4-benzodioxin-2-carbonyl chloride; (2S)-2,3-Dihydro-1,4-benzodioxine-2-carbonyl chloride; 1,4-Benzodioxin-2-carbonyl chloride, 2,3-dihydro-, (S)-; L-1,4-Benzodioxin-2-carbonyl chloride; (S)-2,3-Dihydrobenzo[b][1,4]dioxine-2-carbonyl chloride; 2,3-Dihydro-1,4-benzodioxin-2-carbonyl chloride, (-)-; (S)-2-Carboxy-2,3-dihydro-1,4-benzodioxine chloride
EINECS	Contact for details

Quality Control

Our 1,4-Benzodioxin-2-Carbonyl Chloride, 2,3-Dihydro-, (-)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.