Description

6-Hydroxycholanoic Acid is a hydroxylated bile acid derivative, a key intermediate in the synthesis of more complex steroidal compounds. Its precise chemical structure makes it valuable for research and development in pharmaceutical chemistry, particularly for exploring metabolic pathways and drug mechanisms. This compound is essential for manufacturers and research institutions focused on steroid-based therapeutics, diagnostic agents, and advanced biochemical studies.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel steroid-based drugs and therapeutic agents.
• Biochemical Research: Used in metabolic studies, enzyme inhibition assays, and as a reference standard in analytical laboratories.
• Diagnostic Reagent Development: Serves as a precursor or component in the formulation of diagnostic kits and biomarkers.
• Academic & Industrial R&D: Employed in universities and corporate R&D centers for exploring bile acid chemistry and related biological activities.
• Reference Standard: Utilized in quality control laboratories for HPLC, LC-MS, or NMR method development and validation.

Basic Information

Product Name	6-Hydroxycholanoic Acid
CAS No.	77059-14-4
Molecular Formula	C24H40O4
Molecular Weight	392.57 g/mol
Synonyms	6α-Hydroxycholanoic Acid; 3α,6α,7α-Trihydroxy-5β-cholan-24-oic Acid; 6-Hydroxy-5β-cholan-24-oic Acid; 3α,6α,7α-Trihydroxycholanoic Acid; Hyocholic Acid (6α-isomer); 5β-Cholan-24-oic acid, 3α,6α,7α-trihydroxy-; (3α,5β,6α,7α)-3,6,7-Trihydroxycholan-24-oic Acid
EINECS	Contact for details

Quality Control

Our 6-Hydroxycholanoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). We provide full traceability and Certificates of Analysis (COA) are available upon request to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.