Description

(5A,7B)-7-Hydroxy-3-Oxo-Cholan-24-Oic Acid CAS NO 77059-13-3 is a high-purity bile acid derivative and a key intermediate in the synthesis of pharmaceutical compounds. This compound matters for its role as a crucial building block in the development of therapeutic agents targeting liver and metabolic functions. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on steroid chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of ursodeoxycholic acid (UDCA) analogs and other therapeutic bile acids.
• Biochemical Research: Used as a reference standard and substrate in studies of bile acid metabolism, liver function, and enzyme activity.
• Fine Chemical Synthesis: Serves as a versatile chiral building block for constructing complex steroid-based molecules in organic chemistry.
• Metabolic Pathway Studies: Employed in in vitro and in vivo research to investigate cholesterol homeostasis and lipid digestion.
• Active Pharmaceutical Ingredient (API) Development: Integral to the research and development phase of new drug candidates targeting hepatobiliary diseases.

Basic Information

Product Name	(5A,7B)-7-Hydroxy-3-Oxo-Cholan-24-Oic Acid
CAS No.	77059-13-3
Molecular Formula	C24H38O5
Molecular Weight	406.56 g/mol
Synonyms	7α-Hydroxy-3-oxo-5β-cholan-24-oic Acid; 7α-Hydroxy-3-oxocholanic Acid; 3-Oxo-7α-hydroxy-5β-cholan-24-oic Acid; 3-Keto-7α-hydroxy-5β-cholanoic Acid; 7α-Hydroxy-3-ketocholanic Acid; 7α-Hydroxy-3-oxolithocholic Acid; 7-Hydroxy-3-oxo-5β-cholan-24-oic Acid; 7α-Hydroxy-3-oxo-5β-cholanic Acid
EINECS	Contact for details

Quality Control

Our (5A,7B)-7-Hydroxy-3-Oxo-Cholan-24-Oic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.