Description

Tetrazolo-Oxo-Purine Nucleoside Triphosphate is a chemically modified nucleotide analog of significant interest in advanced biochemical research and development. This compound is valued for its unique structure, which incorporates a tetrazolo-oxo-purine base, offering distinct properties for probing and manipulating nucleic acid systems. It is primarily utilized by researchers and developers in the fields of pharmaceutical discovery, molecular diagnostics, and enzymology who require specialized nucleotide building blocks. Its application is critical for studies involving nucleic acid metabolism, enzyme inhibition, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies, particularly those involving polymerases, kinases, and other nucleotide-processing enzymes.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) precursor in the synthesis of novel antiviral or anticancer nucleoside analogs.
• Molecular Biology: Employed in the study of nucleic acid structure and function, including research into non-canonical base pairing and nucleic acid aptamers.
• Diagnostic Probe Synthesis: Utilized in the development of labeled nucleotides for advanced detection systems in genomics and diagnostic assays.
• Enzyme Mechanism Studies: Acts as a mechanistic probe to investigate the active sites and catalytic pathways of enzymes that utilize ATP or similar triphosphates.

Basic Information

Product Name	Tetrazolo-Oxo-Purine Nucleoside Triphosphate
CAS No.	77044-71-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	8-Azaxanthine nucleoside triphosphate; Tetrazolo[1,5-f]purine nucleoside triphosphate; 8-AzaGMP triphosphate; 8-Azaguanosine-5'-triphosphate analog; TP-Tetrazolo-oxo-purine; Nucleoside-5'-triphosphate, tetrazolo-oxo-purine; GTP analog, tetrazolo-modified
EINECS	Contact for details

Quality Control

Our Tetrazolo-Oxo-Purine Nucleoside Triphosphate is produced under a rigorous quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research and development applications. Certificates of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by NMR/IR/MS), and impurity profiles are available upon request. We adhere to industry best practices to support your critical work in life sciences.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to moisture, heat, or light should be avoided to maintain stability and potency. For long-term storage, consider desiccant and under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or suitable aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.