Description

2-Chromanecarbonylchloride is a versatile and reactive organic intermediate, specifically a chromane-based acid chloride. This compound is valued for its role as a key building block in the synthesis of more complex molecules, enabling the introduction of the chromanecarbonyl moiety. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for constructing novel active ingredients and fine chemicals. Its reactivity makes it essential for amide bond formation and other acylations in specialized organic synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those containing the chromane scaffold which is associated with various biological activities.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the chromane structure can contribute to desired efficacy.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, dyes, and functional materials.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new chemical spaces in medicinal and synthetic chemistry laboratories.
• Peptide Mimetic & Protease Inhibitor Research: The acid chloride functionality is instrumental in creating peptide analogs and enzyme inhibitors for biochemical studies.

Basic Information

Product Name	2-Chromanecarbonylchloride
CAS No.	77039-78-2
Molecular Formula	C10H9ClO2
Molecular Weight	196.63 g/mol
Synonyms	2-Chromancarbonyl Chloride; Chroman-2-carbonyl chloride; 3,4-Dihydro-2H-1-benzopyran-2-carbonyl chloride; 2H-1-Benzopyran-2-carbonyl chloride, 3,4-dihydro-; 2-Chlorocarbonylchroman
EINECS	Contact for details

Quality Control

Every batch of 2-Chromanecarbonylchloride is produced and tested under a strict quality management system to ensure consistency and reliability for your synthetic processes. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.