Description

Cyclobutanecarbonyl Bromide (9Ci) is a versatile and reactive acyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the cyclobutanecarbonyl moiety, a valuable structural motif in medicinal chemistry and materials science. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality raw materials for complex synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) containing cyclobutane rings, which are explored for their unique conformational and metabolic properties.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the cyclobutyl group can enhance biological activity.
• Peptide Mimetics & PROTACs: Employed in the construction of peptide analogs and Proteolysis Targeting Chimeras (PROTACs) for drug discovery programs.
• Material Science Research: Acts as a precursor for monomers or cross-linking agents in the development of specialty polymers with tailored properties.
• Ligand & Catalyst Development: Useful for synthesizing novel ligands and organometallic complexes for catalytic applications.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences sector.

Basic Information

Product Name	Cyclobutanecarbonyl Bromide (9Ci)
CAS No.	76940-04-0
Molecular Formula	C5H7BrO
Molecular Weight	163.01 g/mol
Synonyms	Cyclobutanecarbonyl bromide; Cyclobutanoyl bromide; Cyclobutylcarbonyl bromide; Bromocyclobutyl ketone; 1-Bromo-1-cyclobutanecarboxaldehyde; 76940-04-0; Cyclobutanecarboxylic acid bromide
EINECS	Contact for details

Quality Control

Our Cyclobutanecarbonyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay by GC/HPLC and identity confirmation (IR, NMR), to ensure it meets the high-purity standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical properties is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.