Description

8-Bromoadenosine-3',5'-Cyclic Monophosphate Sodium Salt is a chemically modified, cell-permeable analog of the crucial secondary messenger cyclic adenosine monophosphate (cAMP). This compound matters as a potent and stable activator of protein kinase A (PKA), making it an indispensable tool for probing intracellular signaling pathways in biochemical and pharmacological research. It is primarily needed by researchers in pharmaceutical R&D, academic institutions, and biotechnology companies focused on signal transduction, neuroscience, and metabolic regulation.

Application

• Biochemical Research: A key tool for studying cAMP-dependent protein kinase (PKA) signaling cascades in cell-free systems and cellular models.
• Pharmaceutical Screening: Used in high-throughput assays to identify and characterize novel modulators of the cAMP/PKA pathway for drug discovery.
• Neuroscience Studies: Employed to investigate the role of cAMP in neuronal function, synaptic plasticity, and neurotransmitter release.
• Metabolic Regulation Research: Applied to study the effects of cAMP on hormone action, gene expression, and metabolic enzyme activity.
• Cell Biology: Utilized to induce specific cellular responses, such as differentiation or secretion, by mimicking elevated intracellular cAMP levels.
• Reference Standard: Serves as a high-purity analytical standard for quality control in the production of research biochemicals and assay kits.

Basic Information

Product Name	8-Bromoadenosine-3',5'-Cyclic Monophosphate Sodium Salt
CAS No.	76939-46-3
Molecular Formula	C10H11BrN5NaO6P
Molecular Weight	430.10 g/mol
Synonyms	8-Bromo-cAMP sodium salt; 8-Br-cAMP sodium salt; 8-Bromoadenosine cyclic 3',5'-(hydrogen phosphate) sodium salt; Sodium 8-bromoadenosine 3',5'-cyclic monophosphate; 8-Bromo-cyclic AMP sodium salt; 8-Br-cyclic adenosine monophosphate sodium salt; 8-Bromoadenosine 3',5'-cyclic monophosphate sodium
EINECS	Contact for details

Quality Control

Our 8-Bromoadenosine-3',5'-Cyclic Monophosphate Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.