Description

Cyclopropanecarboxylic Acid, 3-(Chlorocarbonyl)-2,2-Dimethyl-, Methyl Ester (9Ci) is a high-purity, specialized organic ester building block with a reactive chlorocarbonyl group. This compound is valued for its role as a key synthetic intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development teams for constructing cyclopropane-containing frameworks, which are prevalent in active ingredients. The product is supplied with a focus on consistent quality and reliable supply to support critical synthesis workflows.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs) containing the cyclopropane moiety, a common structural feature in various drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropane ring can enhance biological activity and stability.
• Organic Synthesis Reagent: Serves as a versatile reagent in academic and industrial laboratories for constructing complex organic molecules, leveraging its reactive acid chloride functionality.
• Material Science Research: Potential monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Chemical Derivatization: Employed to introduce the 2,2-dimethylcyclopropanecarbonyl group into target molecules for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 3-(Chlorocarbonyl)-2,2-Dimethyl-, Methyl Ester (9Ci)
CAS No.	76842-28-9
Molecular Formula	C8H11ClO3
Molecular Weight	190.62 g/mol
Synonyms	3-(Chlorocarbonyl)-2,2-dimethylcyclopropanecarboxylic acid methyl ester; Methyl 3-(chlorocarbonyl)-2,2-dimethylcyclopropanecarboxylate; 2,2-Dimethylcyclopropane-1,3-dicarboxylic acid 1-methyl ester 3-acid chloride; 1-Methyl 3-chloroformyl-2,2-dimethylcyclopropane-1,3-dicarboxylate; 2,2-Dimethylcyclopropane-1,3-dicarboxylic acid monomethyl ester chloride
EINECS	Contact for details

Quality Control

Our production of Cyclopropanecarboxylic Acid, 3-(Chlorocarbonyl)-2,2-Dimethyl-, Methyl Ester adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques like GC, HPLC, and NMR to ensure identity, purity, and consistency meet the exacting standards required for synthetic intermediates. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature and strong acid/organic solvent properties, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.