Description

Cyclopropanecarbonyl Chloride, 3-Acetyl-2,2-Dimethyl- (9Ci) is a specialized organic intermediate featuring a reactive acid chloride group attached to a substituted cyclopropane ring. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research chemists and process development scientists working on novel active ingredients, where its unique structure enables the introduction of the cyclopropane moiety, a motif known for influencing biological activity and metabolic stability. The CAS number for this compound is 76842-23-4.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing cyclopropane rings for enhanced potency and pharmacokinetic properties.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropane structure can contribute to specific modes of action.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of novel polymers with tailored thermal or mechanical properties.
• Organic Synthesis & Methodology: Employed in academic and industrial R&D for constructing complex molecular architectures, including natural product analogs.
• Ligand and Catalyst Development: Utilized to create novel chiral ligands or organometallic catalysts for asymmetric synthesis.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value specialty chemicals for electronics or performance materials.

Basic Information

Product Name	Cyclopropanecarbonyl Chloride, 3-Acetyl-2,2-Dimethyl- (9Ci)
CAS No.	76842-23-4
Molecular Formula	C8H11ClO2
Molecular Weight	174.62 g/mol
Synonyms	3-Acetyl-2,2-dimethylcyclopropanecarbonyl chloride; 2,2-Dimethyl-3-acetylcyclopropanecarboxylic acid chloride; 1-(2,2-Dimethyl-3-(chlorocarbonyl)cyclopropyl)ethan-1-one; 3-Acetyl-2,2-dimethylcyclopropanecarboxylic acid chloride; 2,2-Dimethyl-3-acetylcyclopropanecarbonyl chloride
EINECS	Contact for details

Quality Control

Our Cyclopropanecarbonyl Chloride, 3-Acetyl-2,2-Dimethyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.