Description

22-Hydroxy-25-Fluorocholesterol is a fluorinated derivative of cholesterol, a key sterol molecule. This compound is of significant interest in biochemical and pharmaceutical research due to its modified structure, which can alter membrane properties and serve as a probe or intermediate. It is primarily utilized by research institutions and pharmaceutical developers working on lipid metabolism, steroid hormone pathways, and novel therapeutic agents. The product is supplied with a focus on high purity and batch-to-batch consistency for reliable experimental results.

Application

• Biochemical Research: Used as a molecular probe to study the effects of fluorination on cholesterol's interaction with cell membranes and lipid rafts.
• Pharmaceutical Intermediates: Serves as a key synthetic building block in the development of novel fluorinated steroid-based therapeutics.
• Metabolic Pathway Studies: Employed in research investigating cholesterol biosynthesis, metabolism, and related enzymatic processes.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Material Science: Investigated for modifying the physical properties of lipid bilayers and biomimetic materials.

Basic Information

Product Name	22-Hydroxy-25-Fluorocholesterol
CAS No.	76752-41-5
Molecular Formula	C27H45FO2
Molecular Weight	420.65 g/mol
Synonyms	25-Fluoro-22-hydroxycholesterol; (22R)-25-Fluorocholest-5-ene-3β,22-diol; 22-Hydroxy-25-fluorocholest-5-en-3β-ol; 25-Fluoro-22-hydroxy-cholesterol; 22-Hydroxy-25-fluoro-cholesterol
EINECS	Contact for details

Quality Control

Our 22-Hydroxy-25-Fluorocholesterol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay purity and identity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.