Description

Cleomycin B2 CAS NO 76741-88-3 is a specialized chemical compound belonging to the cleomycin family of antibiotics, known for its potent biological activity. This product is critical for research and development in the life sciences sector, particularly in the study of novel antimicrobial and antitumor agents. It serves as a key intermediate or reference standard for pharmaceutical companies, academic research institutions, and biotechnology firms engaged in drug discovery and biochemical analysis.

Application

• Pharmaceutical Research: As a reference standard or active pharmaceutical ingredient (API) intermediate in the development of new antibiotic and anticancer therapies.
• Biochemical Studies: For investigating mechanisms of action, DNA interaction, and cytotoxicity in various cell lines.
• Microbiology Research: Used in studies targeting specific bacterial strains to understand and combat antibiotic resistance.
• Academic & Institutional R&D: A vital tool for universities and research institutes conducting fundamental research in medicinal chemistry and molecular biology.
• Quality Control Laboratories: Employed as a certified reference material (CRM) to ensure the purity and potency of related pharmaceutical products.

Basic Information

Product Name	Cleomycin B2
CAS No.	76741-88-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cleomycin B2; Antibiotic U-20,661; U-20661; 7-Deoxy-7-[(1S)-1-hydroxyethyl]-O-6-methyl-L-lyxo-heptopyranosylidene-(1-2-3)-O-β-D-talopyranosyl-(1-4)-2,6-dideoxy-2-methylamino-α-L-talopyranosyl-(1-3)-O-[2,6-dideoxy-2-methylamino-α-L-talopyranosyl-(1-4)]-2,6-dideoxy-2-methylamino-α-L-talopyranosyl-(1-1)-N1-[(3S)-3-amino-3-deoxy-β-D-glucopyranosyl]bleomycinamide; Bleomycin A2 Hydrochloride (component of); (S)-4-Amino-6-[[(2S,3S,4R,5S,6S)-5-[[(2S,3S,4S,5R,6R)-4-[[(2S,3S,4R,5S,6S)-4,5-Dihydroxy-6-methyl-3-(methylamino)tetrahydro-2H-pyran-2-yl]oxy]-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy]-3,4-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy]-2-[[(1S)-1-[[(1S)-1-[[4-[(Aminoiminomethyl)amino]butyl]amino]-3-(3,6-dihydro-6-oxo-2H-pyrimidin-4-yl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-4-oxobutanoic Acid
EINECS	Contact for details

Quality Control

Our Cleomycin B2 is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research applications. All materials are accompanied by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.