Description

[1,1-Bicyclobutyl]-3-Carbonyl Chloride (9Ci) is a specialized, high-purity organic building block characterized by its reactive carbonyl chloride functional group attached to a bicyclobutyl scaffold. This compound matters as a critical intermediate for advanced organic synthesis, enabling the introduction of the unique bicyclobutyl moiety into target molecules, which is valuable for modulating physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those requiring rigid, three-dimensional structural elements.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the bicyclobutyl group can influence biological activity and environmental fate.
• Material Science Research: Employed in the creation of advanced polymers or functional materials with tailored thermal or mechanical properties.
• Organic Synthesis Reagent: Acts as an acylating agent to introduce the [1,1-bicyclobutyl]-3-carbonyl group into amines, alcohols, or other nucleophiles in complex molecule construction.
• Ligand and Catalyst Development: Utilized as a precursor for synthesizing specialized ligands for catalysis or molecular recognition studies.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new chemical space in both university and corporate research laboratories.

Basic Information

Product Name	[1,1-Bicyclobutyl]-3-Carbonyl Chloride (9Ci)
CAS No.	76730-66-0
Molecular Formula	C9H11ClO
Molecular Weight	170.64 g/mol
Synonyms	1,1-Bicyclobutyl-3-carbonyl chloride; 3-(1,1-Bicyclobutyl)carbonyl chloride; Bicyclo[1.1.0]butane-1-carbonyl chloride, 3-substituted; (Bicyclobutyl-1)carbonyl chloride; 76730-66-0 (CAS); 1,1'-Bicyclobutyl-3-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of [1,1-Bicyclobutyl]-3-Carbonyl Chloride (9Ci) is produced and analyzed under strict quality management protocols to ensure consistency and reliability for your synthetic workflows. Our standard grade typically meets a purity specification of ≥95% (by GC or HPLC), but custom purities are available. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C for long-term stability. Keep away from strong bases, alcohols, amines, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.