Description

Cyclobutanecarbonyl Chloride, 3-Ethyl- (9Ci) is a specialized organic acid chloride building block used in advanced synthetic chemistry. This compound is valued for its reactivity as an acylating agent, enabling the efficient introduction of the 3-ethylcyclobutanecarbonyl moiety into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates. Its defined structure facilitates the creation of compounds with specific steric and electronic properties.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the cyclobutane ring can impart unique biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and mechanical properties.
• Chemical Biology & Proteomics: Employed as a reagent for modifying peptides, proteins, or other biomolecules to study function or create bioconjugates.
• Catalyst & Ligand Development: Acts as a precursor for synthesizing novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical manufacturers producing bespoke compounds for client R&D and scale-up projects.

Basic Information

Item	Detail
Product Name	Cyclobutanecarbonyl Chloride, 3-Ethyl- (9Ci)
CAS No.	76730-61-5
Molecular Formula	C7H11ClO
Molecular Weight	146.61 g/mol
Synonyms	3-Ethylcyclobutanecarbonyl chloride; 3-Ethylcyclobutane-1-carbonyl chloride; 1-(Chlorocarbonyl)-3-ethylcyclobutane; 3-Ethyl-1-cyclobutanecarbonyl chloride; Cyclobutanecarbonyl chloride, 3-ethyl-
EINECS	Contact for details

Quality Control

Every batch of Cyclobutanecarbonyl Chloride, 3-Ethyl- (9Ci) is produced and analyzed under strict quality management protocols to ensure consistency and reliability for your critical syntheses. Our standard grade typically meets a purity specification of ≥95% (by GC or HPLC), with rigorous control of key impurities. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and assay results is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.