Description

Thymidine 3':5'-Cyclic Monophosphate Sodium Salt is a high-purity nucleotide derivative, specifically a cyclic monophosphate ester of thymidine. This compound is a critical biochemical reagent valued for its role in cellular signaling research and as a precursor in nucleic acid chemistry. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require reliable, high-quality nucleotide analogs for drug discovery, diagnostic development, and fundamental biochemical studies.

Application

• Biochemical Research: Used as a substrate, inhibitor, or analog in studies of cyclic nucleotide-dependent signaling pathways, phosphodiesterase activity, and protein kinase function.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the synthesis and quality control of novel antiviral and anticancer nucleoside-based therapeutics.
• Diagnostic Reagent Manufacturing: Employed in the formulation of enzyme-linked immunosorbent assays (ELISAs) and other diagnostic kits that detect or quantify cellular response elements.
• Enzymology Studies: Acts as a specific ligand or effector in enzymatic assays to study the kinetics and mechanisms of nucleotidyl cyclases and esterases.
• Cell Culture & Molecular Biology: Utilized in specialized cell culture media or as a component in buffers for investigating cell cycle regulation and nucleotide metabolism.

Basic Information

Product Name	Thymidine 3':5'-Cyclic Monophosphate Sodium Salt
CAS No.	76567-90-3
Molecular Formula	C10H12N2NaO8P
Molecular Weight	342.17 g/mol
Synonyms	Cyclic TMP Sodium Salt; cTMP Na Salt; 3',5'-cTMP Sodium Salt; Thymidine 3',5'-cyclic monophosphate sodium salt; Sodium thymidine 3',5'-cyclic monophosphate; Cyclic thymidylic acid sodium salt; cTMP; Cyclic thymidine monophosphate sodium
EINECS	Contact for details

Quality Control

Our Thymidine 3':5'-Cyclic Monophosphate Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and stringent tests for moisture and endotoxin levels where applicable. We provide full traceability and Certificates of Analysis (COA) are available upon request to ensure compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
pH (1% Solution)	6.0 - 8.0
Endotoxin (where specified)	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.