Description

1-Piperazinecarbonyl Chloride, 4-(1-Oxopropyl)- (9Ci) is a specialized organic building block featuring a reactive acid chloride group and a piperazine core. This compound matters for its role as a key intermediate in the synthesis of complex molecules, enabling the introduction of the piperazinecarbonyl moiety. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the piperazine structure can contribute to biological activity.
• Chemical Research & Development: Serves as a versatile reagent in organic synthesis for creating amide bonds and functionalizing molecules with piperazine derivatives.
• Ligand and Catalyst Preparation: Employed in the development of specialized ligands for metal catalysis or as a precursor for functional materials.
• Custom Synthesis Projects: Utilized by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule assembly under cGMP or non-GMP conditions.

Basic Information

Product Name	1-Piperazinecarbonyl Chloride, 4-(1-Oxopropyl)- (9Ci)
CAS No.	76535-76-7
Molecular Formula	C8H13ClN2O2
Molecular Weight	204.65 g/mol
Synonyms	4-Propionylpiperazine-1-carbonyl chloride; 1-(Propionyl)piperazine-4-carbonyl chloride; 4-Propionyl-1-piperazinecarbonyl chloride; NSC 405124; Piperazine-1-carbonyl chloride, 4-propionyl-; 4-(1-Oxopropyl)-1-piperazinecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarbonyl Chloride, 4-(1-Oxopropyl)- is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.