Description

Uridine-5-Oxyacetic Acid 5'-Monophosphate is a chemically modified nucleotide monophosphate derivative, also known as 5-carboxymethyluridine monophosphate. This compound is a key intermediate and building block in advanced biochemical research and pharmaceutical development. It is primarily utilized by research institutions, diagnostic manufacturers, and companies developing novel therapeutic agents and nucleotide-based technologies.

Application

• Biochemical Research: Serves as a critical precursor and reference standard in the study of RNA modification, enzyme kinetics, and nucleotide metabolism.
• Pharmaceutical Intermediates: Used in the synthesis of novel nucleoside analogs and prodrugs with potential antiviral or anticancer activity.
• Diagnostic Reagent Manufacturing: Employed in the production of specialized reagents and kits for molecular diagnostics and biomarker detection.
• Enzymology Studies: Acts as a substrate or inhibitor for specific enzymes, such as kinases and phosphodiesterases, to elucidate biological pathways.
• Nucleotide Library Synthesis: A valuable component for creating diverse nucleotide libraries used in screening for drug discovery and biotechnology applications.

Basic Information

Product Name	Uridine-5-Oxyacetic Acid 5'-Monophosphate
CAS No.	76343-23-2
Molecular Formula	C12H15N2O11P
Molecular Weight	394.23 g/mol
Synonyms	5-Carboxymethyluridine 5'-Monophosphate; 5-Carboxymethyl-UMP; cm5UMP; Uridine-5-acetic acid 5'-monophosphate; 5-O-Carboxymethyluridine monophosphate; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(phosphonooxy)tetrahydrofuran-2-yl)-5-(carboxymethyl)pyrimidine-2,4(1H,3H)-dione
EINECS	Contact for details

Quality Control

Our Uridine-5-Oxyacetic Acid 5'-Monophosphate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation. Keep the container sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity	As specified per batch

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.