Description

4-Cyclopropylbenzenecarboxylic Acid Chloride is a versatile and reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 4-cyclopropylbenzoyl moiety, a valuable structural motif in medicinal chemistry and material science. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the cyclopropyl group enhances biological activity and stability.
• Liquid Crystal & OLED Material Production: Acts as a building block for creating novel aromatic cores in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Employed to introduce functional aromatic groups into polymer chains, modifying thermal and mechanical properties of engineering plastics and coatings.
• Peptide & Protein Research: Useful as an acylating agent in peptide coupling reactions and for modifying biomolecules in biochemical research.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse R&D projects.

Basic Information

Product Name	4-Cyclopropylbenzenecarboxylic Acid Chloride
CAS No.	76274-94-7
Molecular Formula	C10H9ClO
Molecular Weight	180.63 g/mol
Synonyms	4-Cyclopropylbenzoyl Chloride; p-Cyclopropylbenzoyl Chloride; (4-Cyclopropylphenyl)carbonyl Chloride; Cyclopropanecarboxylic Acid, 4-Chlorocarbonylphenyl Ester; 1-Cyclopropyl-4-(chlorocarbonyl)benzene; Benzoic Acid, 4-cyclopropyl-, chloride
EINECS	Contact for details

Quality Control

Our 4-Cyclopropylbenzenecarboxylic Acid Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, GC, NMR, and FTIR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 2-8°C (refrigerated) or as specified on the label. This compound is hygroscopic (moisture-sensitive) and reacts vigorously with water, alcohols, and strong bases. Keep away from heat, sparks, and open flame. Use under an inert atmosphere (nitrogen/argon) for prolonged storage or handling of opened containers to maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.