Description

1-Piperidinecarbonyl Chloride, 3-Hydroxy- (9Ci) is a specialized organic building block featuring a reactive acid chloride group and a hydroxyl functionality. This dual reactivity makes it a valuable intermediate for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry and fine chemical synthesis. Its structure is ideal for constructing piperidine-based pharmacophores and other advanced chemical entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing modified piperidine scaffolds.
• Medicinal Chemistry Research: Used in high-throughput screening libraries and for structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Peptidomimetic Synthesis: Employed in the creation of peptide analogs and mimetics due to its ability to introduce carbonyl and hydroxyl groups into molecular frameworks.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.
• Agrochemical Research: Acts as an intermediate in the development of novel herbicides, fungicides, and insecticides.

Basic Information

Product Name	1-Piperidinecarbonyl Chloride, 3-Hydroxy- (9Ci)
CAS No.	76263-92-8
Molecular Formula	C7H10ClNO2
Molecular Weight	175.61 g/mol
Synonyms	3-Hydroxypiperidine-1-carbonyl chloride; 3-Hydroxy-1-piperidinecarboxylic acid chloride; 3-Hydroxypiperidine-1-carboxylic acid chloride; 1-Carboxy-3-hydroxypiperidine chloride; 3-Hydroxy-N-carboxypiperidine chloride; 3-Hydroxypiperidine-1-carbonyl chloride; 1-Piperidinecarbonyl chloride, 3-hydroxy-
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarbonyl Chloride, 3-Hydroxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.