Description

3-(4-Trifluoromethyl-Phenoxy)-Azetidine is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the azetidine ring's constrained geometry and the trifluoromethylphenoxy moiety's lipophilicity and metabolic stability. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the design and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for specialized ligands in catalysis or as a scaffold in material science.
• Chemical Biology Probes: Employed in the synthesis of molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring fluorinated, constrained ring systems.

Basic Information

Product Name	3-(4-Trifluoromethyl-Phenoxy)-Azetidine
CAS No.	76263-21-3
Molecular Formula	C10H10F3NO
Molecular Weight	217.19 g/mol
Synonyms	3-[(4-Trifluoromethyl)phenoxy]azetidine; 3-(4-(Trifluoromethyl)phenoxy)azetidine; Azetidine, 3-[(4-(trifluoromethyl)phenoxy]-; 3-(alpha,alpha,α-Trifluoro-p-tolyloxy)azetidine; 3-(4-Trifluoromethylphenoxy)azetidine; 3-(p-Trifluoromethylphenoxy)azetidine
EINECS	Contact for details

Quality Control

Our 3-(4-Trifluoromethyl-Phenoxy)-Azetidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.