Description

Pyridine, 4-Isothiocyanato- (9Ci) is a specialized heterocyclic compound featuring a reactive isothiocyanate functional group attached to the pyridine ring. This molecular architecture makes it a valuable building block and derivatization agent in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting enzyme inhibition or receptor binding.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its reactive site for creating bioactive molecules.
• Bioconjugation & Labeling Reagent: Acts as a derivatizing agent for amines and other nucleophiles in proteins, peptides, or other biomolecules for analytical or diagnostic purposes.
• Material Science Research: Building block for creating functionalized polymers, ligands for metal-organic frameworks (MOFs), or advanced organic electronic materials.
• Chemical Biology Probe: Useful for modifying biomolecules to study biological pathways or for affinity chromatography.
• Cross-linking Agent: Employed in the preparation of modified surfaces, hydrogels, or polymer networks due to its bifunctional reactivity.

Basic Information

Item	Details
Product Name	Pyridine, 4-Isothiocyanato- (9Ci)
CAS No.	76105-84-5
Molecular Formula	C7H4N2S
Molecular Weight	148.18 g/mol
Synonyms	4-Isothiocyanatopyridine; 4-Pyridyl isothiocyanate; p-Isothiocyanatopyridine; 4-Pyridinyl isothiocyanate; 1-Isothiocyanato-4-pyridine; Isothiocyanic acid, 4-pyridyl ester; 4-Pyridine isothiocyanate; 4-PIC
EINECS	Contact for details

Quality Control

Every batch of Pyridine, 4-Isothiocyanato- (9Ci) is produced and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and development applications. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.