Description

3-Chloro-4-Fluoro-1-Benzothiophene-2-Carbonyl Chloride is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. Its value lies in its dual reactive sites, making it a critical intermediate for constructing complex heterocyclic scaffolds. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides with enhanced efficacy.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	3-Chloro-4-Fluoro-1-Benzothiophene-2-Carbonyl Chloride
CAS No.	75998-36-6
Molecular Formula	C9H3Cl2FOS
Molecular Weight	249.09 g/mol
Synonyms	2-Carbonyl Chloride-3-Chloro-4-Fluorobenzothiophene; 3-Chloro-4-fluorobenzo[b]thiophene-2-carbonyl chloride; 3-Chloro-4-fluoro-1-benzothiophene-2-carboxylic acid chloride; 75998-36-6; 3-Chloro-4-fluorothianaphthene-2-carbonyl chloride; Benzothiophene-2-carbonyl chloride, 3-chloro-4-fluoro-; 3-Chloro-4-fluoro-benzo[b]thiophene-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluoro-1-Benzothiophene-2-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.