Description

Grahamimycin B is a specialized antibiotic compound belonging to the macrolide class, valued for its potent biological activity. This high-purity chemical is critical for research and development in the pharmaceutical and life sciences sectors, where precise and reliable materials are paramount. It serves as a key intermediate and reference standard for scientists developing novel therapeutic agents, particularly in the study of antibacterial mechanisms and resistance.

Application

• Pharmaceutical Research & Development: As a reference standard and active pharmaceutical ingredient (API) intermediate in the development of new antibiotic therapies.
• Microbiological Studies: Used in laboratory research to study bacterial growth inhibition, mechanism of action, and resistance patterns of macrolide antibiotics.
• Biochemical Assay Development: Serves as a critical component in high-throughput screening assays and potency tests for drug discovery programs.
• Academic Research: A vital tool for universities and research institutes investigating the synthesis, structure-activity relationships, and metabolic pathways of complex macrolides.
• Quality Control Laboratories: Employed as a certified reference material (CRM) to validate analytical methods and ensure batch-to-batch consistency in API manufacturing.

Basic Information

Product Name	Grahamimycin B
CAS No.	75979-94-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Grahamimycin B; Antibiotic U-62162; U-62162; 75979-94-1; (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclotetradecane-7,15-dione
EINECS	Contact for details

Quality Control

Our Grahamimycin B is manufactured under strict quality management systems to ensure the highest standards of purity and consistency. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with our rigorous specifications. We support cGMP-compliant applications and can provide documentation to meet the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.